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Anti-GABBR2 (Ser783) (Polyclonal), ALEXA Fluor 594

Anti-GABBR2 (Ser783) (Polyclonal), ALEXA Fluor 594 size: 100 microliters 516

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 516
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGABBR2 Ser783
SpecificityThis antibody reacts specifically with GABBR2 (Ser783)
ModificationPhosphorylation
Modification siteSer783
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser783
Gene ID9568
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, Plays a critical role in the fine-tuning of inhibitory synaptic transmission, Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis, muscle relaxation and antinociception, slow wave sleep, stimulates phospholipase A2, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials, Receptor for GABA
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms HG20 GABABR2 GPRC3B
Also known asGABBR2 (Ser783) Polyclonal Antibody
Other nameAnti-GABBR2 (Ser783) Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGABBR2 (Ser783)
Short nameAnti-GABBR2 (Ser783) (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GABBR2 (Ser783) (polyclonal)
Alternative techniquepolyclonals
Identity 4507
Gene GABBR2
Long gene name gamma-aminobutyric acid type B receptor subunit 2
Synonyms gene GPR51
Synonyms gene name 2 , G protein-coupled receptor 51 gamma-aminobutyric acid (GABA) B receptor
Locus 9q22, 33
Discovery year 1999-04-23
GenBank acession AF069755
Entrez gene record 9568
Pubmed identfication 10087195
Classification Gamma-aminobutyric acid type B receptor subunits
Havana BLAST/BLAT OTTHUMG00000020345

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