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Anti-GABPA/NRF2A (Polyclonal), ALEXA Fluor 594

Anti-GABPA/NRF2A (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGABPA/NRF2A
SpecificityThis antibody reacts specifically with GABPA/NRF2A
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GABPA/NRF2A
Gene ID2551
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini, GABP beta, GABP beta is expressed in both the cytoplasm and the nucleus, GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, In primary neuronal cultures, The GABP alpha beta tetrameric complex performs many different functions, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription, both of which can modify GABP-dependent transcription in vitro and in vivo, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, such as stimulating transcription of the adenovirus E4 gene, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, whereas GABP alpha is expressed mainly in the nucleus, The transcription factor GA-binding protein (GABP) is composed of two subunits
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms E4TF1A NFT2 NRF2 E4TF1-60 NRF2A
Also known asGABPA/NRF2A Polyclonal Antibody
Other nameAnti-GABPA/NRF2A Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGABPA/NRF2A
Short nameAnti-GABPA/NRF2A (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GABPA/NRF2A (polyclonal)
Alternative techniquepolyclonals
Identity 4071
Gene GABPA
Long gene name GA binding protein transcription factor alpha subunit
Synonyms gene name GA-binding protein transcription factor, alpha subunit (60kD) GA binding protein transcription factor, alpha subunit 60kDa
Synonyms name human nuclear respiratory factor-2 subunit alpha nuclear respiratory factor 2 alpha subunit
Locus 21q21, 3
Discovery year 1994-01-18
Entrez gene record 2551
Pubmed identfication 8441384
RefSeq identity NM_002040
Classification ETS transcription factor family
Havana BLAST/BLAT OTTHUMG00000078443

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