Name : Anti-GABR B3 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN5577602277
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GABR B3 |
| Specificity | This antibody reacts specifically with GABR B3 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human GABR B3/GABA A Receptor beta 3 |
| Gene ID | 2562 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Both GABAA and GABAC are ligand-gated ion channels, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing, function to catalyze the production of GABA (gamma-aminobutyric acid), glutamate decarboxylases, however, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel, the major inhibitory neurotransmitter in the vertebrate brain, they are structurally and functionally distinct, GABA, GAD-65 and GAD-67 |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | GABA alpha receptor beta-2 subunit, GABAA receptor beta 3 subunit, GABAA receptor subunit beta 3, GABAA receptor subunit beta-3, GABR B3, GBRB3_HUMAN, Gabrb3, Gamma aminobutyric acid GABA A receptor beta 3, Gamma aminobutyric acid receptor subunit beta 3, Gamma-aminobutyric acid receptor subunit beta-3, MGC9051, ECA5 |
| Also known as | GABR B3 Polyclonal Antibody |
| Other name | Anti-GABR B3 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GABR B3 |
| Short name | Anti-GABR B3 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GABR B3 (polyclonal) |
| Alternative technique | polyclonals |