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Anti-GALR3 (Polyclonal), ALEXA Fluor 594

Anti-GALR3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGALR3
SpecificityThis antibody reacts specifically with GALR3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human GALR3
Gene ID8484
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Binding of galanin to galanin receptors results in increased feeding, GALR3 mRNA is highly expressed in the hypothalamus, GALR3 mRNA is widely distributed, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, In human, Like GALR1, Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4, and is expressed to a lesser extent in adrenal gland and pancreas, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, but expressed at low abundance, enhanced opiate analgesia and decreased opiate place preference, impaired learning, pituitary and testis, respectively, the gastrointestinal tract and in the endocrine and exocrine pancreas, the pituitary gland, which are linked to the regulation of neurotransmitter release, which is distributed throughout the central and peripheral nervous system, GALR3 a 368 and 370 amino acid protein in human and rat
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asGALR3 Polyclonal Antibody
Other nameAnti-GALR3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGALR3
Short nameAnti-GALR3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GALR3 (polyclonal)
Alternative techniquepolyclonals
Identity 4134
Gene GALR3
Long gene name galanin receptor 3
Locus 22q13, 1
Discovery year 1998-12-17
GenBank acession AF073799
Entrez gene record 8484
Pubmed identfication 9722565 9832121
Classification Galanin receptors
Havana BLAST/BLAT OTTHUMG00000150658

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