Anti-GAPDH (Polyclonal), ALEXA Fluor 594

Anti-GAPDH (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	GAPDH
Specificity	This antibody reacts specifically with GAPDH
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Cytoplasm
Antigen Source	GAPDH protein of rabbit
Gene ID	2597
Swiss Prot	P04406
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes, DNA replication and apoptosis, Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity), Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate, HDAC2 and PRKDC, Modulates the organization and assembly of the cytoskeleton, Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, Participates in nuclear events including transcription, RNA transport, Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation, respectively, thereby playing a role in glycolysis and nuclear functions, Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Also known as	GAPDH Polyclonal Antibody
Other name	Anti-GAPDH Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	GAPDH
Short name	Anti-GAPDH (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-GAPDH (polyclonal)
Alternative technique	polyclonals
Identity	4141
Gene	GAPDH
Long gene name	glyceraldehyde-3-phosphate dehydrogenase
Synonyms gene	GAPD
Locus	12p13, 31
Discovery year	2001-06-22
GenBank acession	AF261085
Entrez gene record	2597
Pubmed identfication	3170585
RefSeq identity	NM_002046
Havana BLAST/BLAT	OTTHUMG00000137379

Anti-GAPDH (Polyclonal), ALEXA Fluor 594

Anti-GAPDH (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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