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Anti-GAPVD1 (Polyclonal), ALEXA Fluor 594

Anti-GAPVD1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGAPVD1
SpecificityThis antibody reacts specifically with GAPVD1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GAPVD1
Gene ID26130
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis, In addition, There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations, GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF)
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DKFZP434C212 KIAA1521
Also known asGAPVD1 Polyclonal Antibody
Other nameAnti-GAPVD1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGAPVD1
Short nameAnti-GAPVD1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GTPase activating protein and VPS9 domains 1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target GAPVD1 and IDBG-638740 and ENSBTAG00000011544 and 539646, GAPVD1 and IDBG-85167 and ENSG00000165219 and 26130, GTPase activating protein binding, Gapvd1 and IDBG-163056 and ENSMUSG00000026867 and 66691, Plasma membranes, this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006897 and endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0032794 and GTPase activating protein binding and molecular function this GO :0043087 and regulation of GTPase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051223 and regulation of protein transport and biological process, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0032794: GTPase activating protein binding, this GO :0005096: GTPase activator activity, this GO :0005515: protein binding, this GO :0032794: GTPase activating protein binding, GTPase activating protein and VPS9 domains 1
Identity 23375
Gene GAPVD1
Long gene name GTPase activating protein and VPS9 domains 1
Locus 9q33, 3
Discovery year 2005-03-22
Entrez gene record 26130
Classification VPS9 domain containing
Havana BLAST/BLAT OTTHUMG00000020678

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