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Anti-GARNL1 (Polyclonal), ALEXA Fluor 594

Anti-GARNL1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGARNL1
SpecificityThis antibody reacts specifically with GARNL1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GARNL1
Gene ID253959
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information During development, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue, GARNL1 expression decreases, GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes, GARNL1 is imported to the nucleus via dimerization with E12, GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap, GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades, In adult brain, This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12, persisting at high levels only in neurons of the adult brain, GARNL1 is expressed during embryogenesis with E12
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GRIPE DKFZp667F074 KIAA0884 Tulip1 RalGAPalpha1
Also known asGARNL1 Polyclonal Antibody
Other nameAnti-GARNL1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGARNL1
Short nameAnti-GARNL1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GARNL1 (polyclonal)
Alternative techniquepolyclonals
Identity 17770
Gene RALGAPA1
Long gene name Ral GTPase activating protein catalytic alpha subunit 1
Synonyms gene GARNL1
Synonyms gene name GTPase activating RANGAP domain-like 1 GTPase activating Rap/RanGAP domain-like 1
Synonyms name tuberin-like protein 1 GAP-related interacting protein to E12
Locus 14q13, 2
Discovery year 2003-10-09
GenBank acession AK126975
Entrez gene record 253959
Pubmed identfication 19520869
RefSeq identity XM_210022
Havana BLAST/BLAT OTTHUMG00000170619

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