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Anti-GAS2 (Polyclonal), ALEXA Fluor 594

Anti-GAS2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGAS2
SpecificityThis antibody reacts specifically with GAS2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GAS2
Gene ID2620
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues, Gas2, Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts, Gas2 is believed to also be involved in the membrane ruffling process, Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles, Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases, The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells, There is no evidence, a component of the microfilament system, however, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis, lung and kidney, of Gas2 expression in spleen, Gas2 is a 313 amino acid protein encoded by the human gene GAS2
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asGAS2 Polyclonal Antibody
Other nameAnti-GAS2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGAS2
Short nameAnti-GAS2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-growth arrest-specific 2 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target GAS2 and IDBG-36228 and ENSG00000148935 and 2620, GAS2 and IDBG-642237 and ENSBTAG00000021654 and 614840, Gas2 and IDBG-188499 and ENSMUSG00000030498 and 14453, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0016020 and membrane and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, growth arrest-specific 2
Identity 4167
Gene GAS2
Long gene name growth arrest specific 2
Locus 11p14, 3
Discovery year 1997-08-28
GenBank acession BC040470
Entrez gene record 2620
Pubmed identfication 9521882
RefSeq identity NM_177553
Havana BLAST/BLAT OTTHUMG00000166071

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