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Anti-GCAP3 (Polyclonal), ALEXA Fluor 594

Anti-GCAP3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGCAP3
SpecificityThis antibody reacts specifically with GCAP3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GCAP3
Gene ID9626
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure, GCAP3 (Guanylyl cyclase-activating protein 3), GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina, There are two isoforms of GCAP3 that are produced as a result of alternative splicing events, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin, is mediated by guanylate cyclase-activating proteins (GCAP), which increases cGMP concentration, The intracellular stimulation of guanylate cyclase (GC) by calcium
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GCAP3
Also known asGCAP3 Polyclonal Antibody
Other nameAnti-GCAP3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGCAP3
Short nameAnti-GCAP3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GCAP3 (polyclonal)
Alternative techniquepolyclonals
Identity 4680
Gene GUCA1C
Long gene name guanylate cyclase activator 1C
Synonyms name guanylyl cyclase-activating protein 3
Locus 3q13, 13
Discovery year 1999-03-12
GenBank acession AF110002
Entrez gene record 9626
Pubmed identfication 10037746 11860507
RefSeq identity NM_005459
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000159204

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