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Anti-GCOM1 (Polyclonal), ALEXA Fluor 594

Anti-GCOM1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGCOM1
SpecificityThis antibody reacts specifically with GCOM1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GCOM1
Gene ID145781
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information CREB function and gene regulation, Gcom1 (GRINL1A complex locus protein 1), Gcom1 is expressed in small intestine, Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events, also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), both of which contain glutamate-gated, cation-specific ion channels, heart, is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, liver, lung, neural development and neurodegeneration, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor, Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ30973 GRINL1A MYZAP-POLR2M
Also known asGCOM1 Polyclonal Antibody
Other nameAnti-GCOM1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGCOM1
Short nameAnti-GCOM1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GCOM1 (polyclonal)
Alternative techniquepolyclonals
Identity 26424
Gene GCOM1
Long gene name GRINL1A complex locus 1
Synonyms name MYZAP-POLR2M readthrough
Locus 15q21, 3
Discovery year 2008-08-05
Entrez gene record 145781
Pubmed identfication 15233991 18849881
RefSeq identity NM_001018090
Havana BLAST/BLAT OTTHUMG00000176411

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