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Anti-GDF15/MIC-1 (Polyclonal), ALEXA Fluor 594

Anti-GDF15/MIC-1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGDF15/MIC-1
SpecificityThis antibody reacts specifically with GDF15/MIC-1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human GDF-15
Gene ID9518
Swiss ProtQ99988
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues, In general, It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects, they are regulators of cell growth and differentiation in both embryonic and adult tissues, GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53, Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PLAB MIC-1 PDF MIC1 NAG-1 PTGFB
Also known asGDF15/MIC-1 Polyclonal Antibody
Other nameAnti-GDF15/MIC-1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGDF15/MIC-1
Short nameAnti-GDF15/MIC-1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-growth differentiation factor 15/MIC-1 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target Extracellular, GDF-15 and MIC-1 and MIC1 and NAG-1 and PDF and PLAB and PTGFB, GDF15 and IDBG-38078 and ENSG00000130513 and 9518, GDF15 and IDBG-641726 and ENSBTAG00000015618 and 618677, Gdf15 and IDBG-163724 and ENSMUSG00000038508 and 23886, growth factor activity, this GO :0005125 and cytokine activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0008083: growth factor activity, this GO :0008083: growth factor activity, growth differentiation factor 15
Identity 30142
Gene GDF15
Long gene name growth differentiation factor 15
Synonyms name prostate differentiation factor
Locus 19p13, 11
Discovery year 2004-02-12
GenBank acession BC008962
Entrez gene record 9518
Pubmed identfication 11895857 9593718
RefSeq identity NM_004864
Havana BLAST/BLAT OTTHUMG00000183360

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