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Anti-GDF6 (Polyclonal), ALEXA Fluor 594

Anti-GDF6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGDF6
SpecificityThis antibody reacts specifically with GDF6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GDF6
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information (5), GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3), GDF-3 is detectable in bone marrow, GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), GDF-6 and GDF-7 are closely related to GDF-5 (6), GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1), It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation, Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1), Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members, a mutation which affects the length and number of bones in limbs (6), spleen, thereby inducing angiogenesis, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4), 2), Growth/differentiation factors (GDFs) are members of the TGF superfamily (1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BMP13 KFS KFS1
Also known asGDF6 Polyclonal Antibody
Other nameAnti-GDF6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGDF6
Short nameAnti-GDF6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-growth differentiation factor 6 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, DNA-templated and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :1990009 and retinal cell apoptotic process and biological process, Extracellular, GDF6 and IDBG-29375 and ENSG00000156466 and 392255, Gdf6 and IDBG-129105 and ENSMUSG00000051279 and 242316, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0040007 and growth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0008083: growth factor activity and also this GO :0042803: protein homodimerization activity, this GO :0008083: growth factor activity, this GO :0042803: protein homodimerization activity, 29849 and IDBG-645217 and ENSBTAG00000007687 and 407175, growth differentiation factor 6
Identity 4221
Gene GDF6
Long gene name growth differentiation factor 6
Synonyms gene SGM1
Synonyms gene name segmentation syndrome 1
Locus 8q22, 1
Discovery year 1999-04-23
Entrez gene record 392255
Pubmed identfication 10022976 18425797
RefSeq identity NM_001001557
Havana BLAST/BLAT OTTHUMG00000164710

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