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Anti-GDF7 (Polyclonal), ALEXA Fluor 594

Anti-GDF7 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGDF7
SpecificityThis antibody reacts specifically with GDF7
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GDF7
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information (5), GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3), GDF-3 is detectable in bone marrow, GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), GDF-6 and GDF-7 are closely related to GDF-5 (6), GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1), It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation, Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1), Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members, a mutation which affects the length and number of bones in limbs (6), spleen, thereby inducing angiogenesis, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4), 2), Growth/differentiation factors (GDFs) are members of the TGF superfamily (1
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BMP12
Also known asGDF7 Polyclonal Antibody
Other nameAnti-GDF7 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGDF7
Short nameAnti-GDF7 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-growth differentiation factor 7 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target DNA-templated and biological process this GO :0048608 and reproductive structure development and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048853 and forebrain morphogenesis and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060571 and morphogenesis of an epithelial fold and biological process this GO :2001051 and positive regulation of tendon cell differentiation and biological process, Extracellular, GDF7 and IDBG-32594 and ENSG00000143869 and 151449, GDF7 and IDBG-637592 and ENSBTAG00000038224 and 286859, Gdf7 and IDBG-128342 and ENSMUSG00000037660 and 238057, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007411 and axon guidance and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0021509 and roof plate formation and biological process this GO :0021527 and spinal cord association neuron differentiation and biological process this GO :0021915 and neural tube development and biological process this GO :0022612 and gland morphogenesis and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0030901 and midbrain development and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0040007 and growth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045165 and cell fate commitment and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0042803: protein homodimerization activity, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0042803: protein homodimerization activity, growth differentiation factor 7
Identity 4222
Gene GDF7
Long gene name growth differentiation factor 7
Locus 2p24, 1
Discovery year 1999-04-23
GenBank acession AF522369
Entrez gene record 151449
Pubmed identfication 10022976 9808626
RefSeq identity NM_182828
Havana BLAST/BLAT OTTHUMG00000090781

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