Anti-GDN (Polyclonal), ALEXA Fluor 594

Anti-GDN (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	GDN
Specificity	This antibody reacts specifically with GDN
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human GDN/SERPINE2
Gene ID	5270
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimerâ, It is involved in tissue remodeling, PN-1 expression is abundant in the nervous system, Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease, cellular invasiveness, complement activation, including the control of blood coagulation, including thrombin, matrix degradation and tumor growth, plasminogen activators (PA) and plasmin, programmed cell death and development, thereby playing a role in neural injury and repair processes, urokinase, where it inhibits thrombin, &euro, &trade, The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, s disease
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	PN1 GDN PNI nexin
Also known as	GDN Polyclonal Antibody
Other name	Anti-GDN Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	GDN
Short name	Anti-GDN (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-GDN (polyclonal)
Alternative technique	polyclonals
Identity	8951
Gene	SERPINE2
Long gene name	serpin family E member 2
Synonyms gene	PI7
Synonyms gene name	clade E (nexin, clade E (nexin, member 2 , member 2 serpin peptidase inhibitor, plasminogen activator inhibitor type 1), plasminogen activator inhibitor type 1), serine (or cysteine) proteinase inhibitor
Synonyms name	glial-derived nexin 1
Locus	2q36, 1
Discovery year	1994-09-01
GenBank acession	M17783
Entrez gene record	5270
Pubmed identfication	7665170 24172014
RefSeq identity	NM_006216
Classification	Serpin peptidase inhibitors
Havana BLAST/BLAT	OTTHUMG00000133163

Anti-GDN (Polyclonal), ALEXA Fluor 594

Anti-GDN (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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