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Anti-GEFT (Polyclonal), ALEXA Fluor 594

Anti-GEFT (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGEFT
SpecificityThis antibody reacts specifically with GEFT
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GEFT
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain, GEFT is an important regulator of processes involved in axon and dendrite formation, GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers, GEFT seems to be an exchange factor primarily for Rac 1 in neurons, GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation, Involved in skeletal myogenesis, and weakly expressed in small intestine, colon, heart and muscle, liver, placenta and lung, GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GEFT p63RhoGEF
Also known asGEFT Polyclonal Antibody
Other nameAnti-GEFT Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGEFT
Short nameAnti-GEFT (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GEFT (polyclonal)
Alternative techniquepolyclonals
Identity 30275
Gene ARHGEF25
Long gene name Rho guanine nucleotide exchange factor 25
Synonyms gene name Rho guanine nucleotide exchange factor (GEF) 25
Synonyms name RAC/CDC42 exchange factor
Locus 12q13, 3
Discovery year 2010-09-02
Entrez gene record 115557
Pubmed identfication 12547822
RefSeq identity NM_133483
Classification Rho guanine nucleotide exchange factors
Havana BLAST/BLAT OTTHUMG00000152516

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