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Anti-GGT5 light chain (Polyclonal), ALEXA Fluor 594

Anti-GGT5 light chain (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGGT5 light chain
SpecificityThis antibody reacts specifically with GGT5 light chain
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 5 light chain
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma, GGT5 converts Leukotriene C4 to Leukotriene D4, In human serum and tissues there is a marked heterogeneity in GGT, In humans, This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes, convert synthetic substrates that are commonly used to assay GGT, hepatic GGT activity is elevated in some liver diseases, however, it does not, g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GGT-REL
Also known asGGT5 light chain Polyclonal Antibody
Other nameAnti-GGT5 light chain Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGGT5 light chain
Short nameAnti-GGT5 light chain (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GGT5 light epitope (polyclonal)
Alternative techniquepolyclonals
Identity 4260
Gene GGT5
Long gene name gamma-glutamyltransferase 5
Synonyms gene GGTLA1
Synonyms gene name gamma-glutamyltransferase-like activity 1
Locus 22q11, 23
Discovery year 1992-08-24
GenBank acession M64099
Entrez gene record 2687
Pubmed identfication 1676842 8095916 18357469
RefSeq identity NM_004121
Classification Gamma-glutamyltransferases
Havana BLAST/BLAT OTTHUMG00000150796

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