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Anti-GGT6 (Polyclonal), ALEXA Fluor 594

Anti-GGT6 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGGT6
SpecificityThis antibody reacts specifically with GGT6
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GGT6
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Belonging to the gamma-glutamyltranspeptidase family, GGT1 is released into the bloodstream after liver damage, GGT5 converts leukotriene C4 to leukotriene D4, GGT6 (gamma-glutamyltransferase 6), GGT6 exists as two alternatively spliced isoforms, In human serum and in human tissues, In humans, This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion, and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes, convert synthetic substrates that are commonly used to assay GGT, hepatic GGT activity is elevated in some liver diseases, however, is a 493 amino acid single-pass type II membrane protein that cleaves glutathione conjugates, it does not, there is a marked heterogeneity in GGT, Gamma-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ90165
Also known asGGT6 Polyclonal Antibody
Other nameAnti-GGT6 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGGT6
Short nameAnti-GGT6 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GGT6 (polyclonal)
Alternative techniquepolyclonals
Identity 26891
Gene GGT6
Long gene name gamma-glutamyltransferase 6
Synonyms gene name gamma-glutamyltransferase 6 homolog (rat)
Locus 17p13, 2
Discovery year 2005-11-14
GenBank acession AK074646
Entrez gene record 124975
Pubmed identfication 18357469
RefSeq identity NM_153338
Classification Gamma-glutamyltransferases
Havana BLAST/BLAT OTTHUMG00000177827

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