Anti-GJA8 (Polyclonal), ALEXA Fluor 594

Anti-GJA8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	GJA8
Specificity	This antibody reacts specifically with GJA8
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human GJA8/Connexin 50
Gene ID	2703
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	2), Connexin proteins share a common topology of 4 transmembrane alpha-helical domains, Consequently, Each of the approximately 20 connexin isoforms produces channels with distinct permeabilities and electrical and chemical sensitivities, For instance, Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, a cytoplasmic loop, a wide variety of malignant phenotypes associate with decreased connexin expression and gap junction communication, and cytoplasmic N- and C-termini (2), deletion of the gene encoding connexin 50, dependent on the particular connexin that is effected (3, normally expressed in the lens, one connexin usually cannot fully substitute for another (2), produces cataracts, the transmembrane and extracellular regions (2), therefore, though not as severe as with deletion of connexin 46 (4), two extracellular loops, &euro, &euro, &oelig, The connexin family of proteins form hexameric complexes called â, connexonsâ, that facilitate movement of low molecular weight proteins between cells via gap junctions (1)
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	CX50
Also known as	GJA8 Polyclonal Antibody
Other name	Anti-GJA8 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	GJA8
Short name	Anti-GJA8 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-GJA8 (polyclonal)
Alternative technique	polyclonals
Identity	4281
Gene	GJA8
Long gene name	gap junction protein alpha 8
Synonyms gene	CAE1 CZP1 CAE
Synonyms gene name	50kD (connexin 50) gap junction protein, 50kDa , 50kDa (connexin 50) gap junction protein, alpha 8, alpha 8, alpha 8, gap junction protein
Synonyms name	connexin 50
Locus	1q21, 2
Discovery year	1995-11-29
GenBank acession	U34802
Entrez gene record	2703
Pubmed identfication	9497259 7796604
RefSeq identity	NM_005267
Classification	Gap junction proteins
Havana BLAST/BLAT	OTTHUMG00000024085

Anti-GJA8 (Polyclonal), ALEXA Fluor 594

Anti-GJA8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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