Anti-GLDC (Polyclonal), ALEXA Fluor 594

Anti-GLDC (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	GLDC
Specificity	This antibody reacts specifically with GLDC
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human GLDC
Gene ID	2731
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	DLD (known as Protein L) and GLDC (known as Protein P), GCSH (known as Protein H), GCSP (glycine cleavage system P protein) or HYGN1, GLDC (glycine dehydrogenase ), GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T, GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor, Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), all of which work together to catalyze the cleavage and degradation of glycine, also known as GCE, also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms, is a 1, 020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family, The glycine cleavage system is comprised of AMT (known as Protein T)
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	GCSP NKH
Also known as	GLDC Polyclonal Antibody
Other name	Anti-GLDC Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	GLDC
Short name	Anti-GLDC (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-GLDC (polyclonal)
Alternative technique	polyclonals
Identity	4313
Gene	GLDC
Long gene name	glycine decarboxylase
Synonyms gene name	glycine cleavage system protein P) glycine dehydrogenase (decarboxylating) , glycine decarboxylase, glycine dehydrogenase (decarboxylating
Synonyms name	glycine cleavage system protein P glycine dehydrogenase
Locus	9p24, 1
Discovery year	1992-04-08
GenBank acession	D90239
Entrez gene record	2731
Pubmed identfication	1993704 1996985
RefSeq identity	NM_000170
Havana BLAST/BLAT	OTTHUMG00000019524
Locus Specific Databases	LRG_643

Anti-GLDC (Polyclonal), ALEXA Fluor 594

Anti-GLDC (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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