Name : Anti-GLI4 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN8814972982
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GLI4 |
| Specificity | This antibody reacts specifically with GLI4 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human GLI4 |
| Gene ID | 2738 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Belonging to the krueppel C2H2-type zinc-finger protein family, GLI-4, GLI-4 may function as a transcriptional regulator, The gene encoding GLI-4 maps to human chromosome 8, The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, also known as HKR4, effectively activating or repressing the transcription of target genes, houses more than 800 genes and is associated with a variety of diseases and malignancies, is a 376 amino acid protein that localizes to the nucleus and contains seven C2H2-type zinc fingers, most of which encompass some form of transcriptional activation or repression, thereby recruiting histone modifying proteins, which consists of nearly 146 million base pairs, which is thought to interact with KAP1, Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | HKR4 ZNF928 |
| Also known as | GLI4 Polyclonal Antibody |
| Other name | Anti-GLI4 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GLI4 |
| Short name | Anti-GLI4 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GLI4 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 4320 |
| Gene | GLI4 |
| Long gene name | GLI family zinc finger 4 |
| Synonyms gene name | GLI-Kruppel family member GLI4 glioma-associated oncogene family zinc finger 4 |
| Locus | 8q24, 3 |
| Discovery year | 1989-05-29 |
| Entrez gene record | 2738 |
| Pubmed identfication | 2850480 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000164952 |