Name : Anti-GLIS2 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN1571803506
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GLIS2 |
| Specificity | This antibody reacts specifically with GLIS2 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human GLIS2 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | By recruiting the corepressors CtBP1 and HDAC3, GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation, GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of KrÃ, GLIS2 is expressed at high levels in kidney and at low levels in heart, GLIS2 represses the transcriptional activation mediated by â, Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis, lung and placenta, &circ, ¼, «, -catenin in the Wnt pathway, GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family, ppel-like proteins |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | NPHP7 |
| Also known as | GLIS2 Polyclonal Antibody |
| Other name | Anti-GLIS2 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GLIS2 |
| Short name | Anti-GLIS2 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GLIS2 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 29450 |
| Gene | GLIS2 |
| Long gene name | GLIS family zinc finger 2 |
| Synonyms name | nephrocystin-7 |
| Locus | 16p13, 3 |
| Discovery year | 2004-07-16 |
| GenBank acession | AF325914 |
| Entrez gene record | 84662 |
| Pubmed identfication | 11741991 14500813 17618285 |
| RefSeq identity | NM_032575 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000129467 |