Filters

Anti-Glucagon (Polyclonal), ALEXA Fluor 594

Anti-Glucagon (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGlucagon
SpecificityThis antibody reacts specifically with Glucagon
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsSecreted
Antigen SourceKLH conjugated synthetic peptide derived from human Glucagon
Gene ID2641
Swiss ProtP01275
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information A counterregulatory hormone of insulin, CRH, GLP-1 is a potent stimulator of glucose-dependent insulin release, GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity, Have growth-promoting activities on intestinal epithelium, Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation, Inhibits beta cell apoptosis, Inhibits gastric emptying in humans, May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, May play an important role in intestinal mucosal growth in the early period of life, Oxyntomodulin significantly reduces food intake, Play important roles on gastric motility and the suppression of plasma glucagon levels, Plays a key role in nutrient homeostasis, Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes, Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis, Stimulates intestinal glucose transport and decreases mucosal permeability, Suppression of gastric emptying may lead to increased gastric distension, TSH, The gastrointestinal tract, and vasopressin secretion, as well as increasing nutrient disposal, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis, enhancing nutrient assimilation through enhanced gastrointestinal function, from the stomach to the colon is the principal target for GLP-2 action, independent of the actions of insulin, oxytocin, raises plasma glucose levels in response to insulin-induced hypoglycemia, which may contribute to satiety by causing a sensation of fullness, Glucagon plays a key role in glucose metabolism and homeostasis
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GGR
Also known asGlucagon Polyclonal Antibody
Other nameAnti-Glucagon Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGlucagon
Short nameAnti-Glucagon (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Glucagon (polyclonal)
Alternative techniquepolyclonals
Identity 4192
Gene GCGR
Long gene name glucagon receptor
Locus 17q25, 3
Discovery year 1994-03-04
GenBank acession U03469 L20316
Entrez gene record 2642
Pubmed identfication 8020989
RefSeq identity NM_000160
Classification Glucagon receptor family
Havana BLAST/BLAT OTTHUMG00000177914

Similar products

Subscribe to our Newsletter