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anti-GluR1 (phospho Ser845) Antibody

anti-GluR1 (phospho Ser845) Antibody size: 0.15 mL 180

Supplier PROSCIENCE
Price 180
Size 0.15 mL
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Gene info GluR1 is also potentiated by phosphorylation at Ser845, In addition, The AMPAR are comprised of 4 distinct subunits (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain, The GluR1 subunit is widely expressed throughout the nervous system, Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR), phosphorylation of this site has been linked to synaptic plasticity as well and learning and memory, The ion channels activated by glutamate are typically divided into two classes
Gene names AMPA-selective glutamate receptor 1, GluR-1, Glur1, gluR-A, GluA1
Antibodie's labelunlabelled serum
PurityAffinity Purified
Ab raised inRabbit
TypePolyclonal
Spicific toGluR1 antibody is specific for GluR1 phosphorylated at Ser845
AntigenGluR1 (Ser845) polyclonal antibody was made against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser845 of rat GluR1
Immuno application immuno fluorescence, immuno-histo-chemistry, Western Blot
Antibody advice Antibody dilutions and tissue load should be based on tissue type and expected phosphorylation state, Applications include Immunofluorescence (IF), Human, IHC and WB, Immunohistochemistry (IHC) and Western Blots (WB), Immunohistochemistry (IHC) has not yet been determined, Initial recommended range of dilutions: 1:500 to 1:2000, The antibody is purified by sequential chromatography on phospho- and non-phosphopeptide affinity columns, When internally tested under ideal conditions the working dilutions were 1:1000 for IF, mouse and rat have 100% amino acid sequence identity with the antigen used to raise the antibody, Immunolabeling of the GluR1 protein in western blots of rat brain is blocked by the Ser845 phosphopeptide used as antigen but not by the corresponding non-phosphopeptide
Suspention, pH, azide 100 ug per mL BSA and 50% glycerol, 150 mM NaCl, 100 uL in 10 mM HEPES (pH 7, 5)
Keep at Stable for one year, but shorter term storage at &ndash, 20 grades C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol, 80 grades C is recommended, For long term storage &ndash
Works with Mouse, Rat, Human
Omim nr97536283
Ncbi nrP19490
KDa100
Vial with antibodyin solution
NCBI GENE nr50592
GENE symbolGria1
Antigene name AMPA 1, ionotropic, glutamate receptor
SourceRattus norvegicus
Protein nrP19490
Description Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4°
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24°
Gene targetGluR1 (phospho Ser845)
Short nameanti-GluR1 (phospho Ser845) Antibody
Technique antibodies against human proteins, antibodies for, antibody to, Antibody
Alternative nameantibody to-GluR1 (phosphorilated Ser845) (Antibody to)
Alternative techniqueantibodies

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