Filters

Anti-GNRHR2 (Polyclonal), ALEXA Fluor 594

Anti-GNRHR2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGNRHR2
SpecificityThis antibody reacts specifically with GNRHR2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human GNRHR2
Gene IDN/A
Swiss ProtN/A
Applications IF(IHC-P), FCM
Applications with corresponding dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive speciesHuman (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Due to alternative splicing events, GnRHR2 is expressed as two isoforms, GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, GnRHR2 mediates its own receptor activity via association with G proteins, Localized to the cell membrane, This hypothalamic hormone is transported to the pituitary, suggesting a possible role in tumor suppression, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asGNRHR2 Polyclonal Antibody
Other nameAnti-GNRHR2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGNRHR2
Short nameAnti-GNRHR2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GNRHR2 (polyclonal)
Alternative techniquepolyclonals
Identity 16341
Gene GNRHR2
Long gene name gonadotropin releasing hormone receptor 2 (pseudogene)
Synonyms gene name gonadotropin-releasing hormone (type 2) receptor 2
Locus 1q21, 1
Discovery year 2001-09-26
GenBank acession AF403014
Entrez gene record 114814
Pubmed identfication 11707068
RefSeq identity NR_002328
Classification Gonadotropin releasing hormone receptors
Havana BLAST/BLAT OTTHUMG00000013742

Subscribe to our Newsletter