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Anti-GORASP2/Golgi phosphoprotein 6/GRASP55, ALEXA Fluor 594

Anti-GORASP2/Golgi phosphoprotein 6/GRASP55, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGolgi phosphoprotein 6
SpecificityThis antibody reacts specifically with GORASP2/Golgi phosphoprotein 6/GRASP55
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Golgi phosphoprotein 6
Gene ID26003
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2, ERK2 directly phosphorylates GRASP55, GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi, GRASP55 is highly homologous to GRASP65 and contains two PDZ domains, GRASP55 is myristoylated and palmitoylated, The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, Unlike GRASP65, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4), suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5), the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1), which is phosphorylated in mitotic cells, 3), The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GRASP55 GRS2 GOLPH6
Also known asGORASP2/Golgi phosphoprotein 6/GRASP55 Antibody
Other nameAnti-GORASP2/Golgi phosphoprotein 6/GRASP55
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetGORASP2/Golgi phosphoprotein 6/GRASP55
Short name Fluor 594, Anti-GORASP2/Golgi phosphoprotein 6/GRASP55
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GORASP2/vesicle packing phosphoprotein 6/GRASP55
Identity 17500
Gene GORASP2
Long gene name golgi reassembly stacking protein 2
Synonyms gene name 55 kDa golgi reassembly stacking protein 2, 55kDa , golgi reassembly stacking protein 2
Locus 2q31, 1
Discovery year 2002-05-23
Entrez gene record 26003
Pubmed identfication 10487747
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000154072

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