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Anti-GOT2 (Polyclonal), ALEXA Fluor 594

Anti-GOT2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGOT2
SpecificityThis antibody reacts specifically with GOT2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GOT2
Gene ID2806
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, High levels are also found after myocardial infarction, In liver about 80% of the enzyme activity is mitochondrial in origin, Serum GOT [with SGPT] levels are usually elevated in states of hepatocellular injury (injury to the liver cells), The 2 isoenzymes are homodimeric, The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene, the highest levels are associated with hepatitis of a viral origin, when SGPT levels are lower, whereas in serum the enzyme activity is largely cytosolic, GOT2 [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate dependent enzyme which exists in both mitochondrial and cytosolic forms
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms mitAAT KATIV KAT4 KYAT4
Also known asGOT2 Polyclonal Antibody
Other nameAnti-GOT2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGOT2
Short nameAnti-GOT2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GOT2 (polyclonal)
Alternative techniquepolyclonals
Identity 4433
Gene GOT2
Long gene name glutamic-oxaloacetic transaminase 2
Synonyms gene name glutamic-oxaloacetic transaminase 2, mitochondrial , mitochondrial (aspartate aminotransferase 2) glutamic-oxaloacetic transaminase 2
Synonyms name kynurenine aminotransferase IV aspartate aminotransferase 2 aspartate transaminase 2
Locus 16q21
Discovery year 2001-06-22
Entrez gene record 2806
Pubmed identfication 17442055
Havana BLAST/BLAT OTTHUMG00000133769

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