Name : Anti-GPCR6A/GPCR33 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2465640063
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GPCR6A/GPCR33 |
| Specificity | This antibody reacts specifically with GPCR6A/GPCR33 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human GPCR6A/GPCR33 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | GPRC6A also acts as a receptor for amino acids, GPRC6A is a member of the G protein-coupled receptor 3 family, GPRC6A is expressed at high levels in liver, GPRC6A senses changes in the extracellular concentration of calcium ions, Its affinity for amino acids suggests that it may act as a regulatory component of the urea cycle, L-Arg and L-ornithine, Osteocalin stimulates the activity of GPRC6A in the presence of calcium, The activity of GPRC6A is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system, This receptor is activated by both amino acids and extracellular concentration of calcium ions, and at lower levels in kidney, lung, skeletal muscle and brain, spleen and heart, suggesting that it may mediate extracellular calcium-sensing responses in osteoblasts, with a preference for basic amino acids such as L-Lys, GPRC6A (G protein-coupled receptor family C group 6 member A) is a 928 amino acid protein encoded by the mouse Gprc6a gene |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | G protein coupled receptor 33, G protein coupled receptor family C group 6 member A, G-protein coupled receptor GPCR33, G-protein coupled receptor family C group 6 member A, GPC6A_HUMAN, GPCR, GPCR 33, GPCR 6A, GPCR33, GPR C6A, GPRC 6A, OTTHUMP00000017075, gprc6a, hGPCR 33, hGPCR33, hGPRC6A, 3, bA86F4 |
| Also known as | GPCR6A/GPCR33 Polyclonal Antibody |
| Other name | Anti-GPCR6A/GPCR33 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GPCR6A/GPCR33 |
| Short name | Anti-GPCR6A/GPCR33 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GPCR6A/GPCR33 (polyclonal) |
| Alternative technique | polyclonals |