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Anti-GPNMB (Polyclonal), ALEXA Fluor 594

Anti-GPNMB (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGPNMB
SpecificityThis antibody reacts specifically with GPNMB
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human GPNMB
Gene ID10457
Swiss ProtQ14956
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information GPNMB may be involved in growth delay and reduction of metastatic potential, GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], a melanocyte-specific protein, The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms NMB HGFIN
Also known asGPNMB Polyclonal Antibody
Other nameAnti-GPNMB Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGPNMB
Short nameAnti-GPNMB (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-glycoprotein (transmembrane) nmb (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target BT, GPNMB and IDBG-9627 and ENSG00000136235 and 10457, Gpnmb and IDBG-146080 and ENSMUSG00000029816 and 93695, HGFIN and NMB, Plasma membranes, heparin binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005178 and integrin binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0030282 and bone mineralization and biological process this GO :0042470 and melanosome and cellular component, this GO :0005178: integrin binding, this GO :0005178: integrin binding and also this GO :0008201: heparin binding, this GO :0008201: heparin binding, 99652 and IDBG-630320 and ENSBTAG00000000604 and 509600, glycoprotein (transmembrane) nmb
Identity 4462
Gene GPNMB
Long gene name glycoprotein nmb
Synonyms gene name glycoprotein (transmembrane) nmb
Synonyms name transmembrane glycoprotein glycoprotein NMB glycoprotein nmb-like protein osteoactivin hematopoietic growth factor inducible neurokinin-1 glycoprotein nonmetastatic melanoma protein B
Locus 7p15, 3
Discovery year 1999-10-26
GenBank acession X76534
Entrez gene record 10457
Pubmed identfication 7814155
RefSeq identity NM_001005340
Havana BLAST/BLAT OTTHUMG00000022811

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