Anti-GPR12 (Polyclonal), ALEXA Fluor 594

Anti-GPR12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	GPR12
Specificity	This antibody reacts specifically with GPR12
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human G protein coupled receptor 12
Gene ID	2835
Swiss Prot	N/A
Applications	IF(IHC-P), FCM
Applications with corresponding dilutions	IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated, GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication, GPR12 is a 334 amino acid peptide that is expressed primarily in brain, GPR12 is coupled to an inhibitory G protein, It positively influences differentiation and maturation of post-mitotic neurons, These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure, and it may promote the growth of neuronal precursor cells, particularly in regions where neuronal differentiation takes place, G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation)
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	GPCR21 PPP1R84
Also known as	GPR12 Polyclonal Antibody
Other name	Anti-GPR12 Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	GPR12
Short name	Anti-GPR12 (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-GPR12 (polyclonal)
Alternative technique	polyclonals
Identity	4466
Gene	GPR12
Long gene name	G protein-coupled receptor 12
Synonyms name	protein phosphatase 1, regulatory subunit 84
Locus	13q12, 13
Discovery year	1995-01-24
GenBank acession	U18548
Entrez gene record	2835
Pubmed identfication	8262253 8530049
Classification	Class A orphans , Protein phosphatase 1 regulatory subunits G protein-coupled receptors
Havana BLAST/BLAT	OTTHUMG00000016620

Anti-GPR12 (Polyclonal), ALEXA Fluor 594

Anti-GPR12 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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