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Anti-GPR120 (Polyclonal), ALEXA Fluor 594

Anti-GPR120 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGPR120
SpecificityThis antibody reacts specifically with GPR120
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsExtracellular
Antigen SourceKLH conjugated synthetic peptide derived from human G protein coupled receptor 120
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Consequently, FFAs act as signaling molecules and are an important energy source, GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying, GLP-1 belongs to the class of molecules known as the incretins, GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids), One such response occurs when dietary FFAs stimulate GPR120, They also employ various physiological responses through their GPCRs, This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes, which are associated with insulin secreted from the pancreas as a result of food intake, GPR120
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms PGR4
Also known asGPR120 Polyclonal Antibody
Other nameAnti-GPR120 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGPR120
Short nameAnti-GPR120 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GPR120 (polyclonal)
Alternative techniquepolyclonals
Identity 19061
Gene FFAR4
Long gene name free fatty acid receptor 4
Synonyms gene GPR129 GPR120 O3FAR1
Synonyms gene name G protein-coupled receptor 129 G protein-coupled receptor 120 omega-3 fatty acid receptor 1
Locus 10q23, 33
Discovery year 2003-08-22
Entrez gene record 338557
Pubmed identfication 20471368 19723586 15619630 20813258
RefSeq identity NM_181745
Classification Free fatty acid receptors
Havana BLAST/BLAT OTTHUMG00000034409

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