Name : Anti-GPR125 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN9997482028
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GPR125 |
| Specificity | This antibody reacts specifically with GPR125 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human GPR125 |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Considered a novel orphan adhesion-type G-protein-coupled receptor, Four isoforms of GPR125 exists due to alternative splicing events, G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, GPR125 (G protein-coupled receptor 125), GPR125 has five leucine rich repeats (LRR), GPR125 may play a functional role in choroidal and hippocampal response to brain injury, It is also suggested that GPR125 may be a marker for spermatogonial stem cells, also known as PGR21 or TEM5L, also known as seven transmembrane receptors, an immunoglobulin (Ig) domain and a GPS domain, comprise a superfamily of proteins that play a role in many different stimulus-response pathways, heptahelical receptors or 7TM receptors, is a 1, such as hormones and neurotransmitters, 321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily, G protein-coupled receptors (GPRs) |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ38547 PGR21 |
| Also known as | GPR125 Polyclonal Antibody |
| Other name | Anti-GPR125 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GPR125 |
| Short name | Anti-GPR125 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GPR125 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 13839 |
| Gene | ADGRA3 |
| Long gene name | adhesion G protein-coupled receptor A3 |
| Synonyms gene | GPR125 |
| Synonyms gene name | G protein-coupled receptor 125 |
| Locus | 4p15, 2 |
| Discovery year | 2003-02-25 |
| GenBank acession | AK095866 |
| Entrez gene record | 166647 |
| Pubmed identfication | 12565841 25713288 |
| Classification | I-set domain containing Adhesion G protein-coupled receptors, subfamily A |
| Havana BLAST/BLAT | OTTHUMG00000160926 |