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Anti-GPR17 (Polyclonal), ALEXA Fluor 594

Anti-GPR17 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGPR17
SpecificityThis antibody reacts specifically with GPR17
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human G protein coupled receptor 17
Gene ID2840
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information GPR17, GPR17, GPR17 is thought to play a role in mediating neuronal death, In some neurons, Two named isoforms of GPR17 exist as a result of alternative splicing events, Upon brain injury, While GPR17 is expressed in kidney, a membrane receptor for uracil nucleotide and CysLTs, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), heart and umbilical vein endothelial cells, increase significantly at the site of damage, infiltrating the lesioned area, is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins, is upregulated as well, it is expressed in the highest levels in the brain, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, G protein-coupled receptor 17
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asGPR17 Polyclonal Antibody
Other nameAnti-GPR17 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGPR17
Short nameAnti-GPR17 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-G protein-coupled receptor 17 (polyclonal)
Alternative techniquepolyclonals
Alternative to gene target GPR17 and IDBG-639124 and ENSBTAG00000006261 and 782442, GPR17 and IDBG-69246 and ENSG00000144230 and 2840, Gpr17 and IDBG-133208 and ENSMUSG00000052229 and 574402, Plasma membranes, chemokine receptor activity, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity, this GO :0004950: chemokine receptor activity, G protein-coupled receptor 17
Identity 4471
Gene GPR17
Long gene name G protein-coupled receptor 17
Locus 2q14, 3
Discovery year 1995-11-21
Entrez gene record 2840
Pubmed identfication 8558062
Classification Class A orphans , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000131533

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