Name : Anti-GPRC5B (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7302724591
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | GPRC5B |
| Specificity | This antibody reacts specifically with GPRC5B |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human G protein coupled receptor family C group 1 member B |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P), FCM |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | G protein-coupled receptors (GPCRs or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins, GPRC5B is an orphan receptor member of the G protein-coupled receptor 3 family, GPRC5B is highly expressed in kidney, Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery, This retinoic acid-inducible G protein-coupled receptor provides evidence for a possible interaction between retinoid and G protein signaling pathways, and has moderate expression in brain, and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and termination, heart, pancreas and testis, prostate, retinoic acid-induced gene 2 protein) is a 403 amino acid protein encoded by the human GPRC5B gene, small intestine and spleen, GPRC5B (G protein-coupled receptor family C group 5 member B |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RAIG-2 |
| Also known as | GPRC5B Polyclonal Antibody |
| Other name | Anti-GPRC5B Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | GPRC5B |
| Short name | Anti-GPRC5B (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-GPRC5B (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 13308 |
| Gene | GPRC5B |
| Long gene name | G protein-coupled receptor class C group 5 member B |
| Synonyms gene name | G protein-coupled receptor, class C, family C, family C, group 1, group 5, group 5, member B , member B G protein-coupled receptor, member B G protein-coupled receptor |
| Locus | 16p12, 3 |
| Discovery year | 2000-01-11 |
| GenBank acession | AF202640 |
| Entrez gene record | 51704 |
| Pubmed identfication | 10493829 10783259 |
| Classification | Class C orphans , G protein-coupled receptors |
| Havana BLAST/BLAT | OTTHUMG00000131460 |