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Anti-GRAMD2 (Polyclonal), ALEXA Fluor 594

Anti-GRAMD2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGRAMD2
SpecificityThis antibody reacts specifically with GRAMD2
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GRAMD2
Gene ID196996
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region, Encoding more than 700 genes, In cases of Prader-Willi syndrome, In the case of Angelman syndrome, Marfan syndrome is associated with chromosome 15 through the FBN1 gene, Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation, which is encoded by chromosome 15, GRAMD2 is a 354 amino acid single-pass membrane protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 15q23
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asGRAMD2 Polyclonal Antibody
Other nameAnti-GRAMD2 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGRAMD2
Short nameAnti-GRAMD2 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GRAMD2 (polyclonal)
Alternative techniquepolyclonals
Identity 27287
Gene GRAMD2
Long gene name GRAM domain containing 2
Locus 15q23
Discovery year 2005-11-02
GenBank acession AK002016
Entrez gene record 196996
Pubmed identfication 12477932
RefSeq identity NM_001012642
Classification GRAM domain containing
Havana BLAST/BLAT OTTHUMG00000172708

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