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Anti-GTP binding protein REM1, ALEXA Fluor 594

Anti-GTP binding protein REM1, ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGTP binding protein REM1
SpecificityThis antibody reacts specifically with GTP binding protein REM1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GTP binding protein REM1
Gene ID28954
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Among these are nonconservative amino acid substitutions within guanine nucleotide binding and hydrolysis domains, GEM/kir, It has been reported that the GTP-bound form of a related Ras-like GTPase, REM, REM is phosphorylated in vivo and has been shown to interact with several 14-3-3 isoforms, The reduced channel activities are the result of a decreased a-subunit expression at the plasma membrane, There are data that suggest that REM similarly regulates Ca2+ channel expression, This inhibition of L-type Ca2+ channels prevents Ca2+-triggered exocytosis in hormone-secreting cells, and a conserved C-terminal sequence thought to mediate membrane association but lacking a classical isoprenylation motif, extended N- and C-termini, inhibits high-voltage activated Ca2+ channel activities by interacting directly with the ?subunit, is most highly expressed in cardiac muscle and is expressed at more moderate levels in lung, kidney and skeletal muscle, unique effector domains, with a predicted molecular weight of 32, 9 kDa, REM (Rad and Gem related GTP binding protein) is a member of the Rad/Gem/Kir subfamily of Ras-like GTPases and shares with other members of this subfamily some unusual structural features
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GES
Also known asGTP binding protein REM1 Antibody
Other nameAnti-GTP binding protein REM1
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetGTP binding protein REM1
Short name Fluor 594, Anti-GTP binding protein REM1
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GTP binding protein REM1
Identity 15922
Gene REM1
Long gene name RRAD and GEM like GTPase 1
Synonyms gene REM
Synonyms gene name RAS (RAD and GEM)-like GTP-binding
Synonyms name GTPase GES
Locus 20q11, 21
Discovery year 2001-06-21
GenBank acession AF152863
Entrez gene record 28954
Pubmed identfication 10831614 14623965 22076634
RefSeq identity NM_014012
Classification RGK type GTPase family
Havana BLAST/BLAT OTTHUMG00000032168

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