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Anti-GTP cyclohydrolase 1 (Polyclonal), ALEXA Fluor 594

Anti-GTP cyclohydrolase 1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideGTP cyclohydrolase 1
SpecificityThis antibody reacts specifically with GTP cyclohydrolase 1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human GTP-CH-1
Gene ID2643
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions, Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, and tryptophan hydroxylases, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis, tyrosine, 8-dihydroneopterin triphosphate, GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms GTPCH1 DYT5a
Also known asGTP cyclohydrolase 1 Polyclonal Antibody
Other nameAnti-GTP cyclohydrolase 1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetGTP cyclohydrolase 1
Short nameAnti-GTP cyclohydrolase 1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-GTP cyclohydrolase 1 (polyclonal)
Alternative techniquepolyclonals
Identity 4193
Gene GCH1
Long gene name GTP cyclohydrolase 1
Synonyms gene GCH DYT5 DYT14
Synonyms gene name dystonia 14
Synonyms name dopa-responsive dystonia
Locus 14q22, 2
Discovery year 1988-05-11
GenBank acession U19523
Entrez gene record 2643
Pubmed identfication 7874165 8695054
Havana BLAST/BLAT OTTHUMG00000029754
Locus Specific Databases BIOMDBdb: Database of Mutations Causing BH4 Deficiencies and other PND

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