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Anti-HB-EGF (Polyclonal), ALEXA Fluor 594
Anti-HB-EGF (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489
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BIOSS POLYCLONAL ANTIBODIES
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489
Size
100 microliters
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| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | HB-EGF |
| Specificity | This antibody reacts specifically with HB-EGF |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Extracellular |
| Antigen Source | KLH conjugated synthetic peptide derived from human HB-EGF/DTSF |
| Gene ID | 1839 |
| Swiss Prot | Q99075 |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Also acts as a diphtheria toxin receptor, ERBB2 and ERBB4, It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF, It is mitogenic for fibroblasts, May be involved in macrophage-mediated cellular proliferation, Promotes smooth muscle cell proliferation, Required for normal cardiac valve formation and normal heart function, but not endothelial cells, Growth factor that mediates its effects via EGFR |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | DTS, DTSF, HBEGF, HEGFL, Proheparin-binding EGF-like growth factor, DTR |
| Also known as | HB-EGF Polyclonal Antibody |
| Other name | Anti-HB-EGF Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HB-EGF |
| Short name | Anti-HB-EGF (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HB-epidermal growth factor (polyclonal) |
| Alternative technique | polyclonals |
| Alternative to gene target | DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0050730 and regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051048 and negative regulation of secretion and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0090279 and regulation of calcium ion import and biological process this GO :0090370 and negative regulation of cholesterol efflux and biological process this GO :1900127 and positive regulation of hyaluronan biosynthetic process and biological process this GO :2000008 and regulation of protein localization to cell surface and biological process this GO :2000060 and positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process, EGF and IDBG-34100 and ENSG00000138798 and 1950, Egf and IDBG-193432 and ENSMUSG00000028017 and 13645, Extracellular, HOMG4 and URG, this GO :0000186 and activation of MAPKK activity and biological process this GO :0001525 and angiogenesis and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005154 and epidermal growth factor receptor binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006260 and DNA replication and biological process this GO :0007165 and signal transduction and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007262 and STAT protein import into nucleus and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010800 and positive regulation of peptidyl-threonine phosphorylation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0021940 and positive regulation of cerebellar granule cell precursor proliferation and biological process this GO :0030168 and platelet activation and biological process this GO :0030297 and transmembrane receptor protein tyrosine kinase activator activity and molecular function this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0035413 and positive regulation of catenin import into nucleus and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045741 and positive regulation of epidermal growth factor-activated receptor activity and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045893 and positive regulation of transcription, this GO :0005154: epidermal growth factor receptor binding, this GO :0005154: epidermal growth factor receptor binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0030297: transmembrane receptor protein tyrosine kinase activator activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0030297: transmembrane receptor protein tyrosine kinase activator activity, transmembrane receptor protein tyrosine kinase activator activity, epidermal growth factor |