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Anti-HCN3 (Polyclonal), ALEXA Fluor 594

Anti-HCN3 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHCN3
SpecificityThis antibody reacts specifically with HCN3
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HCN3
Gene ID57657
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information HCN channels are expressed in the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, HCN3 contains a segment characterized by a series of positively charged amino acids at every third position, In the brain, The HCN family consists of four members (HCN1-4), The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart, This region designated S4 is likely to be the voltage sensor of the protein, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides, each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif, heart, respectively, thalamus and testis, Hyperpolarization-activated
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms KIAA1535
Also known asHCN3 Polyclonal Antibody
Other nameAnti-HCN3 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHCN3
Short nameAnti-HCN3 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HCN3 (polyclonal)
Alternative techniquepolyclonals
Identity 19183
Gene HCN3
Long gene name hyperpolarization activated cyclic nucleotide gated potassium channel 3
Synonyms gene name hyperpolarization activated cyclic nucleotide-gated potassium channel 3
Locus 1q22
Discovery year 2002-09-02
GenBank acession AB040968
Entrez gene record 57657
Pubmed identfication 16382102
RefSeq identity NM_020897
Classification Cyclic nucleotide gated channels
Havana BLAST/BLAT OTTHUMG00000035872

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