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Anti-HDAC8 (Polyclonal), ALEXA Fluor 594

Anti-HDAC8 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHDAC8
SpecificityThis antibody reacts specifically with HDAC8
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locations Nucleus, Cytoplasm
Antigen SourceKLH conjugated synthetic peptide derived from human HDAC8
Gene ID55869
Swiss ProtQ9BY41
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin, H2B, H3 and H4), Histone deacetylases act via the formation of large multiprotein complexes, Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, May play a role in smooth muscle cell contractility, cell cycle progression and developmental events, Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms RPD3
Also known asHDAC8 Polyclonal Antibody
Other nameAnti-HDAC8 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHDAC8
Short nameAnti-HDAC8 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HDAC8 (polyclonal)
Alternative techniquepolyclonals
Identity 13315
Gene HDAC8
Long gene name histone deacetylase 8
Synonyms gene HDACL1 WTS MRXS6
Synonyms gene name histone deacetylase-like 1 Wilson-Turner X-linked mental retardation syndrome
Locus Xq13, 1
Discovery year 2000-11-28
GenBank acession AF230097
Entrez gene record 55869
Pubmed identfication 10756090 10922473 22889856
RefSeq identity NM_018486
Classification X-linked mental retardation Histone deacetylases, class I
Havana BLAST/BLAT OTTHUMG00000021814
Locus Specific Databases Mental Retardation database

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