Name : Anti-HELZ (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN3756469483
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | HELZ |
| Specificity | This antibody reacts specifically with HELZ |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human HELZ |
| Gene ID | N/A |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Expressed ubiquitously during embryonic development, HELZ (helicase with zinc finger), HELZ is thought to function as an RNA helicase that modifies RNA structure and plays a role in the development of multiple organs and tissues within the developing embryo, RNA helicases alter the conformation of RNA, a process which changes the biological activity of the RNA molecule, also known as DHRC or HUMORF5, effectively separating two annealed nucleic acid strands, is a 1, specifically by unwinding double-stranded RNA regions to yield single RNA strands, 942 amino acid nuclear protein that contains one C3H1-type zinc finger and belongs to the RNA helicase superfamily, Helicases comprise a class of enzymes that function as motor proteins which move along nucleic acid phosphodiester bonds |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA0054 HUMORF5 DHRC |
| Also known as | HELZ Polyclonal Antibody |
| Other name | Anti-HELZ Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HELZ |
| Short name | Anti-HELZ (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HELZ (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 16878 |
| Gene | HELZ |
| Long gene name | helicase with zinc finger |
| Synonyms name | down-regulated in human cancers |
| Locus | 17q24, 2 |
| Discovery year | 2002-02-15 |
| GenBank acession | D29677 |
| Entrez gene record | 9931 |
| Pubmed identfication | 10471385 12691822 |
| RefSeq identity | NM_014877 |
| Classification | UPF1 like RNA helicases Zinc fingers CCCH-type |
| Havana BLAST/BLAT | OTTHUMG00000179555 |