Anti-Heparanase (Polyclonal), ALEXA Fluor 594

Anti-Heparanase (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	Heparanase
Specificity	This antibody reacts specifically with Heparanase
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	N/A
Antigen Source	KLH conjugated synthetic peptide derived from human Heparanase
Gene ID	N/A
Swiss Prot	N/A
Applications	IF(IHC-P)
Applications with corresponding dilutions	IF(IHC-P)(1:50-200)
Cross reactive species	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and an 8 kDa subunit, Heparanase is highly expressed in myeloid leukocytes (i, Heparanase plays an important role in ECM degradation, Human heparanase was found to be upregulated in various types of primary tumors, It is produced as a latent 65 kDa precursor and proteolytically processed to its active form, Upon degradation, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival, facilitating the migration and extravasations of tumor cells and inflammatory leukocytes, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis, neutrophils) in platelets and in human placenta, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix, Heparanase is an endo-beta-D-glucuronidase, e
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	HPA2 HPR2 HPSE2
Also known as	Heparanase Polyclonal Antibody
Other name	Anti-Heparanase Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	Heparanase
Short name	Anti-Heparanase (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Heparanase (polyclonal)
Alternative technique	polyclonals
Identity	12521
Gene	UFS
Long gene name	heparanase 2 (inactive)
Synonyms gene name	urofacial syndrome heparanase 2
Locus	10q24, 2
Discovery year	2002-09-02
GenBank acession	AF282885
Entrez gene record	60495
Pubmed identfication	11027606 20560210 9199567 20576607
RefSeq identity	NM_021828
Havana BLAST/BLAT	OTTHUMG00000018880

Anti-Heparanase (Polyclonal), ALEXA Fluor 594

Anti-Heparanase (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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