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Anti-HER2 receptor(1A4) Monoclonal, ALEXA Fluor 594

Anti-HER2 receptor(1A4) Monoclonal, ALEXA Fluor 594 size: 139 microliters 489

Supplier BIOSS MONOCLONAL ANTIBODIES
Price 489
Size 139 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated withALEXA FLUOR 594
Host organismMouse (Mus musculus)
Target Protein/PeptideHER2 receptor
SpecificityHighly specific antibody against HER2 receptor
ModificationNot modified
ClonalityMonoclonal Antibodies
Clone1A4
Concentration1ug per 1ul
Antigen SourceKLH conjugated synthetic peptide derived from human HER2 receptor
Gene ID2064
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross Reactive speciesHuman (Homo sapiens)
Cross Reactive Species detailsNo significant cross reactivity is observed
Background information Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, Alternative splicing results in several additional transcript variants, Amplification and/or overexpression of this gene has been reported in numerous cancers, However, Ile654/Ile655, Jul 2008], This protein has no ligand binding domain of its own and therefore cannot bind growth factors, [provided by RefSeq, including breast and ovarian tumors, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, shown here, some encoding different isoforms and others that have not been fully characterized, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase, with the most common allele, This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases
Purification methodPurified by Protein G
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, Aqueous buffered solution containing 100ug/ml BSA, C for 12 months
Excitation emission590nm/617nm
Synonyms NEU HER-2 CD340 HER2
Alternative name 1 594 Conjugated, ALEXA FLUOR®, HER2 receptor(1A4) Monoclonal Antibody
Alternative name 2 ALEXA FLUOR 594 Conjugated, HER2 receptor(1A4) Monoclonal anti-
Advisory For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, specificity and reactivity, Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetHER2 receptor(1A4) Monoclonal
Short name Fluor 594, Anti-HER2 receptor(1A4) Monoclonal
TechniqueMonoclonals or monoclonal antibodies
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HER2 receptor(1A4) monoclonal
Identity 3430
Gene ERBB2
Long gene name erb-b2 receptor tyrosine kinase 2
Synonyms gene NGL
Synonyms gene name v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms name neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2
Locus 17q12
Discovery year 2001-06-22
GenBank acession X03363
Entrez gene record 2064
RefSeq identity NM_004448
Classification CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000179300
Locus Specific Databases LRG_724

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