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Anti-HEXB chain B (Polyclonal), ALEXA Fluor 594

Anti-HEXB chain B (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHEXB chain B
SpecificityThis antibody reacts specifically with HEXB chain B
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HEXB chain B
Gene ID3074
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II), Beta-hexosaminidase is composed of two subunits, Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases, Jul 2008], Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses, [provided by RefSeq, alpha and beta, and other molecules containing terminal N-acetyl hexosamines, catalyzes the degradation of the ganglioside GM2, together with the cofactor GM2 activator protein, which are encoded by separate genes, Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asHEXB chain B Polyclonal Antibody
Other nameAnti-HEXB chain B Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHEXB chain B
Short nameAnti-HEXB chain B (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HEXB epitope B (polyclonal)
Alternative techniquepolyclonals
Identity 4879
Gene HEXB
Long gene name hexosaminidase subunit beta
Synonyms gene name hexosaminidase B (beta polypeptide)
Synonyms name beta-hexosaminidase subunit beta
Locus 5q13, 3
Discovery year 2001-06-22
GenBank acession M13519
Entrez gene record 3074
Pubmed identfication 2579389 3013851
RefSeq identity NM_000521
Havana BLAST/BLAT OTTHUMG00000102057
Locus Specific Databases HEXB Locus Database

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