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Anti-HEXDC (Polyclonal), ALEXA Fluor 594

Anti-HEXDC (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHEXDC
SpecificityThis antibody reacts specifically with HEXDC
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HEXDC
Gene ID284004
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome, Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides, N-acetyl-beta-galactosaminidase, The gene encoding HEXDC maps to human chromosome 17, Two key tumor suppressor genes are associated with chromosome 17, also known as hexosaminidase D, beta-hexosaminidase D, colon, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family, namely, p53 and BRCA1, prostate gland and fallopian tubes, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, HEXDC
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms FLJ23825
Also known asHEXDC Polyclonal Antibody
Other nameAnti-HEXDC Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHEXDC
Short nameAnti-HEXDC (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HEXDC (polyclonal)
Alternative techniquepolyclonals
Identity 26307
Gene HEXDC
Long gene name hexosaminidase D
Synonyms gene name catalytic domain) containing , hexosaminidase (glycosyl hydrolase family 20
Synonyms name cytosolic , hexosaminidase D
Locus 17q25, 3
Discovery year 2006-01-12
GenBank acession AK074405
Entrez gene record 284004
Pubmed identfication 19040401
RefSeq identity NM_173620
Havana BLAST/BLAT OTTHUMG00000178836

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