Name : Anti-HEXDC (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN2005855519
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | HEXDC |
| Specificity | This antibody reacts specifically with HEXDC |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | N/A |
| Antigen Source | KLH conjugated synthetic peptide derived from human HEXDC |
| Gene ID | 284004 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome, Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides, N-acetyl-beta-galactosaminidase, The gene encoding HEXDC maps to human chromosome 17, Two key tumor suppressor genes are associated with chromosome 17, also known as hexosaminidase D, beta-hexosaminidase D, colon, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family, namely, p53 and BRCA1, prostate gland and fallopian tubes, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, HEXDC |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FLJ23825 |
| Also known as | HEXDC Polyclonal Antibody |
| Other name | Anti-HEXDC Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HEXDC |
| Short name | Anti-HEXDC (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HEXDC (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 26307 |
| Gene | HEXDC |
| Long gene name | hexosaminidase D |
| Synonyms gene name | catalytic domain) containing , hexosaminidase (glycosyl hydrolase family 20 |
| Synonyms name | cytosolic , hexosaminidase D |
| Locus | 17q25, 3 |
| Discovery year | 2006-01-12 |
| GenBank acession | AK074405 |
| Entrez gene record | 284004 |
| Pubmed identfication | 19040401 |
| RefSeq identity | NM_173620 |
| Havana BLAST/BLAT | OTTHUMG00000178836 |