Name : Anti-HEXIM1 (Polyclonal), ALEXA Fluor 594
Supplier : BIOSS POLYCLONAL ANTIBODIES
Price :489
SKU : GEN7813274049
| Type | Conjugated Primary Antibody |
| Conjugated with | 594, ALEXA FLUOR® |
| Host organism | Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide | HEXIM1 |
| Specificity | This antibody reacts specifically with HEXIM1 |
| Modification | No modification has been applied to this antibody |
| Modification site | None |
| Clonality | Polyclonal Antibody |
| Clone | Polyclonal Antibodies |
| Concentration | 1ug per 1ul |
| Subcellular locations | Nucleus, Cytoplasm |
| Antigen Source | KLH conjugated synthetic peptide derived from human HEXIM1/EDG1 |
| Gene ID | 10614 |
| Swiss Prot | N/A |
| Applications | IF(IHC-P) |
| Applications with corresponding dilutions | IF(IHC-P)(1:50-200) |
| Cross reactive species | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details | However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information | Cdk9, Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, P-TEFb is composed of a catalytic subunit, The C-terminal domains of HEXIM proteins interact directly with each other, This complex regulates eukaryotic gene expression at the level of elongation, Via these domains, and either Cyclin T1 or T2 as a regulatory subunit, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle, Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK |
| Purification method | Purified by Protein A |
| Storage | 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CLP-1 HIS1 MAQ1 EDG1 |
| Also known as | HEXIM1 Polyclonal Antibody |
| Other name | Anti-HEXIM1 Polyclonal |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties | For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HEXIM1 |
| Short name | Anti-HEXIM1 (Polyclonal) Fluor 594 |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label | ALEXA |
| Alternative name | ALEXA Fluor 594, antibody to-HEXIM1 (polyclonal) |
| Alternative technique | polyclonals |
| Identity | 24953 |
| Gene | HEXIM1 |
| Long gene name | hexamethylene bisacetamide inducible 1 |
| Locus | 17q21, 31 |
| Discovery year | 2005-06-27 |
| GenBank acession | AB021179 |
| Entrez gene record | 10614 |
| Pubmed identfication | 12119119 12832472 |
| RefSeq identity | NM_006460 |
| Havana BLAST/BLAT | OTTHUMG00000180112 |