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Anti-hHBrk1 (Polyclonal), ALEXA Fluor 594

Anti-hHBrk1 (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Supplier BIOSS POLYCLONAL ANTIBODIES
Price 489
Size 100 microliters
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptidehHBrk1
SpecificityThis antibody reacts specifically with hHBrk1
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human hHBrk1
Gene ID55845
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex, Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons, HSPC300 is thought to localize to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis, HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization, In Drosophila, In addition, In mice, The WAVE complex includes five proteins, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions, it is thought to have the same or similar functions in many different organisms, one of which is HSPC300, suggesting that decreased levels of HSPC300 may be associated with tumor suppression, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent, the WAVE/ARC pathway may affect the development of the nervous system, the knockout of the WAVE complex leads to learning and memory defects, HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms BRK1_HUMAN, C3ORF10 GENE, C3orf10 chromosome 3 open reading frame 10, Chromosome 3 open reading frame 10, HSPC300, MDS027, Probable protein BRICK1, hHBrk1, Brk1-like
Also known ashHBrk1 Polyclonal Antibody
Other nameAnti-hHBrk1 Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targethHBrk1
Short nameAnti-hHBrk1 (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-hHBrk1 (polyclonal)
Alternative techniquepolyclonals

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