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Anti-HIF2 alpha (Polyclonal), ALEXA Fluor 594

Anti-HIF2 alpha (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHIF2 alpha
SpecificityThis antibody reacts specifically with HIF2 alpha
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsNucleus
Antigen SourceKLH conjugated synthetic peptide derived from mouse HIF2 Alpha
Gene ID13819
Swiss ProtP97481
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP3, Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters, Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity), May also play a role in the formation of the endothelium that gives rise to the blood brain barrier, Potent activator of the Tie-2 tyrosine kinase expression, Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung, Transcription factor involved in the induction of oxygen regulated genes
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms EPAS-1, Endothelial PAS domain-containing protein 1, Epas1, HIF-1-alpha-like factor, HIF-2-alpha, HIF-2alpha, HIF-related factor, HIF2-alpha, HIF2A, HRF, Hypoxia-inducible factor 2-alpha, MOP2, bHLHe73, mHLF, HLF
Also known asHIF2 alpha Polyclonal Antibody
Other nameAnti-HIF2 alpha Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHIF2 alpha
Short nameAnti-HIF2 alpha (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HIF2 a (polyclonal)
Alternative techniquepolyclonals

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