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Anti-Hippocalcin (Polyclonal), ALEXA Fluor 594

Anti-Hippocalcin (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHippocalcin
SpecificityThis antibody reacts specifically with Hippocalcin
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human Hippocalcin
Gene IDN/A
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information In order to regulate kinase and phospholipase activity, The hippocalcin protein is highly conserved in mouse, The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation, Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging, with increased expression observed in hippocampal pyramidal cells, Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Also known asHippocalcin Polyclonal Antibody
Other nameAnti-Hippocalcin Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHippocalcin
Short nameAnti-Hippocalcin (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-Hippocalcin (polyclonal)
Alternative techniquepolyclonals
Identity 5144
Gene HPCA
Long gene name hippocalcin
Locus 1p35, 1
Discovery year 1994-12-14
GenBank acession BC001777
Entrez gene record 3208
Pubmed identfication 8166736 9931466
RefSeq identity NM_002143
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000004017

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