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Anti-HIRA (Polyclonal), ALEXA Fluor 594

Anti-HIRA (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489
Size 100 microliters
TypeConjugated Primary Antibody
Conjugated with 594, ALEXA FLUOR®
Host organismRabbit (Oryctolagus cuniculus)
Target Protein/PeptideHIRA
SpecificityThis antibody reacts specifically with HIRA
ModificationNo modification has been applied to this antibody
Modification siteNone
ClonalityPolyclonal Antibody
ClonePolyclonal Antibodies
Concentration1ug per 1ul
Subcellular locationsN/A
Antigen SourceKLH conjugated synthetic peptide derived from human HIRA/DGGR1
Gene ID7290
Swiss ProtN/A
ApplicationsIF(IHC-P)
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
Cross reactive species Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, Orthologs of this gene in flies, These foci likely mediate the irreversible cell cycle changes that occur in senescent cells, This gene plays an important role in the formation of the senescence-associated heterochromatin foci, and insufficient production of the gene may disrupt normal embryonic development, yeast and plants are necessary for the formation of transcriptionally silent heterochomatin, 3 in nucleosomes, The HIRA gene encodes a histone chaperone that preferentially places the variant histone H3
Purification methodPurified by Protein A
Storage 50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission590nm/617nm
Synonyms DGCR1 TUP1
Also known asHIRA Polyclonal Antibody
Other nameAnti-HIRA Polyclonal
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
PropertiesFor facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
GroupPolyclonals and antibodies
About The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene targetHIRA
Short nameAnti-HIRA (Polyclonal) Fluor 594
Technique Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different 
LabelALEXA
Alternative name ALEXA Fluor 594, antibody to-HIRA (polyclonal)
Alternative techniquepolyclonals
Identity 4916
Gene HIRA
Long gene name histone cell cycle regulator
Synonyms gene TUPLE1
Synonyms gene name HIR (histone cell cycle regulation defective) homolog A (S, cerevisiae) , cerevisiae) HIR histone cell cycle regulation defective homolog A (S
Synonyms name DiGeorge critical region gene 1
Locus 22q11, 21
Discovery year 1994-04-21
GenBank acession X75296
Entrez gene record 7290
Pubmed identfication 8111380 7633437 9731536
RefSeq identity NM_003325
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000150134

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