Anti-HLA-DR (Polyclonal), ALEXA Fluor 594

Anti-HLA-DR (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

Price 489

Size 100 microliters

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Type	Conjugated Primary Antibody
Conjugated with	594, ALEXA FLUOR®
Host organism	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide	HLA-DR
Specificity	This antibody reacts specifically with HLA-DR
Modification	No modification has been applied to this antibody
Modification site	None
Clonality	Polyclonal Antibody
Clone	Polyclonal Antibodies
Concentration	1ug per 1ul
Subcellular locations	Extracellular
Antigen Source	KLH conjugated synthetic peptide derived from human HLA-DRA
Gene ID	3122
Swiss Prot	P01903
Applications	IF(IHC-P), FCM
Applications with corresponding dilutions	IF(IHC-P)(1:50-200), FCM(1:20-100)
Cross reactive species	Human (Homo sapiens)
Cross Reactive Species details	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information	Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5, Exon 1 encodes the leader peptide, It plays a central role in the immune system by presenting peptides derived from extracellular proteins, Jul 2008], The alpha chain is approximately 33-35 kDa and its gene contains 5 exons, This class II molecule is a heterodimer consisting of an alpha and a beta chain, [provided by RefSeq, and exon 4 encodes the transmembrane domain and the cytoplasmic tail, both anchored in the membrane, dendritic cells, exons 2 and 3 encode the two extracellular domains, macrophages), HLA-DRA is one of the HLA class II alpha chain paralogues
Purification method	Purified by Protein A
Storage	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission	590nm/617nm
Synonyms	CD74
Also known as	HLA-DR Polyclonal Antibody
Other name	Anti-HLA-DR Polyclonal
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties	For facs or microscopy Alexa 1 conjugate
Conjugation	Alexa Fluor
Group	Polyclonals and antibodies
About	The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot
Gene target	HLA-DR
Short name	Anti-HLA-DR (Polyclonal) Fluor 594
Technique	Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different
Label	ALEXA
Alternative name	ALEXA Fluor 594, antibody to-Human leukocyte antigen-DR (polyclonal)
Alternative technique	polyclonals
Identity	2866
Gene	DHLAG
Long gene name	CD74 molecule
Synonyms gene name	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) CD74 molecule, class II invariant chain , major histocompatibility complex
Synonyms name	HLA-DR-gamma Ia-associated invariant chain gamma chain of class II antigens MHC HLA-DR gamma chain
Locus	5q33, 1
Discovery year	1986-01-01
Entrez gene record	972
Pubmed identfication	6324166 3001652
RefSeq identity	NM_004355
Classification	CD molecules
Havana BLAST/BLAT	OTTHUMG00000163559

Anti-HLA-DR (Polyclonal), ALEXA Fluor 594

Anti-HLA-DR (Polyclonal), ALEXA Fluor 594 size: 100 microliters 489

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